Insights into eye evolution

Discussion in 'Physiology and Biology' started by OB, Mar 23, 2006.

  1. OB

    OB Colossal Squid Staff Member Moderator

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    Abstract of interesting research; could as well have been posted in the F&H section :wink:

    CENTER FOR INFORMATION BIOLOGY AND DNA DATA BANK OF JAPAN
    Laboratory for DNA Data Analysis - Takashi Gojobori Group

    Comparative analysis of gene expression for convergent evolution of camera eye between octopus and human

    Atsushi Ogura, Kazuho Ikeo and Takashi Gojobori

    --Although the camera eye of the octopus is very similar to that of humans, phylogenetic and embryological analyses have suggested that their camera eyes have been acquired independently. It has been known as a typical example of convergent evolution. To study the molecular basis of convergent evolution of camera eyes, we conducted a comparative analysis of gene expression in octopus and human camera eyes. We sequenced 16,432 ESTs of the octopus eye, leading to 1052 nonredundant genes that have matches in the protein database. Comparing these 1052 genes with 13,303 already-known ESTs of the human eye, 729 (69.3%) genes were commonly expressed between the human and octopus eyes. On the contrary, when we compared octopus eye ESTs with human connective tissue ESTs, the expression similarity was quite low. To trace the evolutionary changes that are potentially responsible for camera eye formation, we also compared octopus-eye ESTs with the completed genome sequences of other organisms. We found that 1019 out of the 1052 genes had already existed at the common ancestor of bilateria, and 875 genes were conserved between humans and octopuses. It suggests that a larger number of conserved genes and their similar gene expression may be responsible for the convergent evolution of the camera eye.
     
  2. Tintenfisch

    Tintenfisch Architeuthis Staff Member Moderator

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    Wow, will definitely check this one out in full! Thanks! :thumbsup:
     
  3. monty

    monty Colossal Squid Staff Member Supporter

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    Is there a reference for journal, volume, etc, for this, or do I need to use scholar.google.com or something to find this?
     
  4. OB

    OB Colossal Squid Staff Member Moderator

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    Sorry if I caused a little confusion here: It's just an overview of their current research focus, so it's best to contact them directly to ask for list of relevant pub's. I will PM you the address of the first named offer, cheers,

    Olaf

    PS: Please find additional info over here
     

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